厉害了,我的THIS(上)|iGEM Competition Bronze Award

By Friday January 14th, 2022Student Achievements

又是一年国际基因工程机器大赛(iGEM)!往年清华附中国际部都与清华附中共同组队参赛,国际部今年次独立组队,以THIS-China战队参赛,与全球顶级名校学生同台竞技。THIS-China团队此次的参赛项目为“通过大肠杆菌构建传感器检测口腔内牙菌斑的数量”,在经过一系列紧张的备战与激烈的角逐之后,THIS-China团队表现优异,在来自世界各地的300多所学校中脱颖而出,斩获大赛铜奖!

Another year of the International Genetically Engineered Machine Competition (iGEM)! THIS used to form the team together with the Tsinghua University High School for previous competitions. This year, THIS first formed THIS-China team to participate in the competition, and competed with students from top high schools around the world. With tireless preparation and fierce competition, THIS-China excelled in the final presentation, and was selected from more than 300 schools for the Bronze Award. THIS-China team project was “Detecting the number of dental plaque in oral cavity by constructing sensor based on E.coli “, which won the unanimous recognition and praise of the judges and experts.

 

赛事介绍

国际基因工程机器大赛是2003年由麻省理工大学创办的生物学领域最权威的赛事,每年吸引包括牛津、剑桥、哈佛、耶鲁等世界顶尖高校超过3000位世界各地的学生学者参加。The international genetic engineering machine competition (iGEM) is one of the best competitions in the field of biology founded by MIT in 2003. It attracts more than 3000 students from all over the world each year, including Oxford, Cambridge, Harvard, Yale. 

Ben Hwang

Devin Chen

Gavin Wang

Hanlin Wang

Kevin Hou

Kelly Chen

Richard Hou

 

今年清华附中国际部THIS-China战队的项目目标是在牙菌斑形成之前提前检测牙菌斑可能的存在,牙菌斑就像是由不同细菌组成的“细菌社区”,它们会附着在牙齿导致各种牙齿疾病。在本项目中,学生们构建了一种大肠杆菌生物传感器,用于检测导致牙菌斑的致病菌变形链球菌产出的信号短肽CSP。其原理是通过颜色降解的显示方式来检测患者口腔中的变形链球菌的数量。

The project goal is to detect the possible existence of dental plaque before the formation of dental plaque. Dental plaque is like a “bacterial community” composed of different bacteria, which will adhere to the teeth and lead to various dental diseases. In this project, we constructed an E. coli biosensor to detect the signal short peptide CSP produced by Streptococcus mutans, which causes dental plaque. The number of Streptococcus mutans in the patient’s mouth was detected by the display of color degradation.

 

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Very good education video, and appreciate the mentioning of shortcomings faced during the research. Congratulations team for the great effort.

参赛作品具有非常好的教育意义。赞赏清华附中国际部学生团队提到了研究过程中面临的短板,祝贺团队的巨大努力获得成功!

A promising topic about the point-of-care testing of dental problems. If it finally works, it will have a large market and a bright future. Keep on going!

关于牙齿的护理问题是很有前途的话题。如果该项目在未来最终实现,它将有很大的市场潜力和光明的未来。清华附中国际部学生团队继续努力吧!

This is a clever and interesting use of synthetic biology. You also did a solid job documenting your work. The promotion video was humorous and very engaging.

这是合成生物学的一次巧妙而有趣的应用。清华附中国际部学生团队在项目记录有非常好的表现。项目视频很幽默,也很有吸引力。

THIS-China provides a good project, which will be really helpful for dentists in the future. Good luck with continuing this project, especially in the field of hardware development.

清华附中国际部学生团队提供了一个有借鉴意义的项目,对未来的牙医来说确实有帮助。希望学生们继续研究这个项目,特别是在硬件开发方面。

A good presentation for a general audience. -The presentation had clear and well-made animations, and described the project well, which includes experimental goals and process, and human-practices collaborations.

清华附中国际部学生团队的演讲视频非常清晰、制作也很精良。视频很好地描述了该项目的实验目标和过程,以及实践合作。

 

Richard  Hou 

iGEM was definitely an incredible, memorable, but roundabout experience for me. As being the leader of THIS-China, our iGEM team, I had gain valuable insight throughout this project. First of all, iGEM as competition pushes me to learn academically, from the basic synthetic biology knowledge to designing a unique project then to doing the actual lab work. While at the same time, it also teaches me valuable day-to-day skills, like how to be a leader to communicate and lead the team, how to make surveys and videos, and even how to communicate with strangers to look for collaborations. From this project, I have also explored the importance of dental health, which a lot of people are not aware of them. That is why we have decided to do this project and spread awareness to the community.

对我来说,iGEM是一次不可思议且令人难忘的经历。作为THIS-China的队长,我从整个项目中获益匪浅宝贵的启示。首先,iGEM比赛激励我专注于专业知识的学习,从基本的合成生物学知识到设计一个独特的项目,再到实际实验。同时,它教会了我宝贵的日常技能,包括资料搜集和视频制作,团队领导力和沟通能力以及拓展寻求合作的能力。从这个项目中,我也意识到了牙齿健康的重要性,这一点在日常生活往往会被忽略。这也是我们决定做这个项目的初衷,我们希望能又更多人意识到这个问题。

 

在备战和比赛的过程中,同学们不仅收获了学科知识,增进了团队合作,更有机会结识不同国家和地区顶级名校的师生、专家学者,极大拓展了同学们的视野。赛后,老师们也鼓励大家进一步将这个项目整理成论文发表在国际有权威影响力的期刊上,也可以尝试申请国家发明专利。这既是新的挑战,又是对大家所做的任务进行梳理和总结的好机会。During the process of preparation and competition, the students not only gained academic knowledge and enhanced teamwork, but also had the opportunity to meet teachers and students, experts and scholars from top schools in different countries and regions, which greatly expanded their horizons. After the competition, they are also encouraged to organize this project into papers to publish in international authoritative journals, or to apply for national invention patents at the same time. This is both a new challenge for the students and a good opportunity to sort out and summarize the project they have done.为了在日常生活中更好地普及生物科学知识,为清华附中大家庭贡献自己的一份力量, THIS-China团队在赛前特地在小学部和初中部为同学们开展了科学活动和实验工作坊,我们将在下篇中为大家精彩呈现,敬请期待!

In order to popularize the biological science knowledge for daily life and make contributions to our THIS family, THIS-China team conducted a series of science activities and experimental workshops for students in primary and secondary divisions before the competition. Let’s look forward to the next article.

 

 

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