Another year of the International Genetically Engineered Machine Competition (iGEM)! THIS used to form the team together with the Tsinghua University High School for previous competitions. This year, THIS first formed THIS-China team to participate in the competition, and competed with students from top high schools around the world. With tireless preparation and fierce competition, THIS-China excelled in the final presentation, and was selected from more than 300 schools for the Bronze Award. THIS-China team project was “Detecting the number of dental plaque in oral cavity by constructing sensor based on E.coli “, which won the unanimous recognition and praise of the judges and experts.
The project goal is to detect the possible existence of dental plaque before the formation of dental plaque. Dental plaque is like a “bacterial community” composed of different bacteria, which will adhere to the teeth and lead to various dental diseases. In this project, we constructed an E. coli biosensor to detect the signal short peptide CSP produced by Streptococcus mutans, which causes dental plaque. The number of Streptococcus mutans in the patient’s mouth was detected by the display of color degradation.
Very good education video, and appreciate the mentioning of shortcomings faced during the research. Congratulations team for the great effort.
A promising topic about the point-of-care testing of dental problems. If it finally works, it will have a large market and a bright future. Keep on going!
This is a clever and interesting use of synthetic biology. You also did a solid job documenting your work. The promotion video was humorous and very engaging.
THIS-China provides a good project, which will be really helpful for dentists in the future. Good luck with continuing this project, especially in the field of hardware development.
A good presentation for a general audience. -The presentation had clear and well-made animations, and described the project well, which includes experimental goals and process, and human-practices collaborations.
iGEM was definitely an incredible, memorable, but roundabout experience for me. As being the leader of THIS-China, our iGEM team, I had gain valuable insight throughout this project. First of all, iGEM as competition pushes me to learn academically, from the basic synthetic biology knowledge to designing a unique project then to doing the actual lab work. While at the same time, it also teaches me valuable day-to-day skills, like how to be a leader to communicate and lead the team, how to make surveys and videos, and even how to communicate with strangers to look for collaborations. From this project, I have also explored the importance of dental health, which a lot of people are not aware of them. That is why we have decided to do this project and spread awareness to the community.
In order to popularize the biological science knowledge for daily life and make contributions to our THIS family, THIS-China team conducted a series of science activities and experimental workshops for students in primary and secondary divisions before the competition. Let’s look forward to the next article.